You can do this using the realtime-sync set-startpoint command. For example:

bin/realtime-sync set-startpoint \
     --hostname sync.example.com \
     --port 636 \
     --useSSL \
     --trustStorePath config/truststore \
     --bindDN "cn=Directory Manager" \
     --bindPasswordFile directory-manager-password.txt \
     --pipe-name "LDAP Source to SCIMv2 Destination" \
     --end-of-changelog \
     --no-prompt